واکسن تب زرد

Laboratory confirmed transmission of 17DD yellow fever vaccine virus via breast-feeding has been documented. Yellow fever vaccine was administered to a nursing mother 15 days postpartum. She was exclusively breast-feeding her newborn. Eight days after maternal vaccination, the infant developed a fever, was irritable, refused to nurse, then was hospitalized for seizures the next day. Yellow fever virus specific to the vaccine and IgM antibodies were detected in the newborn CSF. The child was discharged after 24 days in the hospital; growth and neurodevelopment were normal through 6 months of age. Breast-feeding is contraindicated by the manufacturer, particularly in infants <9 months of age. Breast-feeding does not adversely affect immunization.